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But when the problem becomes frequent or continues for an extended time, you should see a doctor. Levitra had no effect on the pharmacodynamics of glyburide (glucose and insulin concentrations) and warfarin (prothrombin time or other pharmacodynamic parameters). Studies in human liver microsomes showed that vardenafil is metabolized primarily by cytochrome P450 (CYP) isoforms 3A4/5, and to a lesser degree by CYP2C9.

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Many other medicines may alter the blood levels of vardenafil, and vice versa. Tell your healthcare provider about all medicines that you take or have recently taken. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, buy xanax without prescrition and other supplements you are using. Erectile dysfunction (ED) represents a multifaceted condition with profound implications for both physiological and psychological health.

The most common side effect with Levitra (seen in more than 1 patient in 10) is headache. For the full list of all side effects reported with Levitra, see the package leaflet. You should also stop these medications and call your doctor right away if you have vision loss. If you’re having chest pain and have taken Viagra in the past 24 hours or Cialis in the past 48 hours, don’t take nitroglycerin. Call for an EMS and make sure you or someone with you tells them which ED medicine you took.
Placebo-controlled trials suggested a dose effect in the incidence of some adverse reactions (headache, flushing, dyspepsia, nausea, and rhinitis) over the 5 mg, 10 mg, and 20 mg doses of Levitra. All these are medical emergencies, and if priapism is left untreated, it could result in permanent erectile dysfunction. Rest assured that most of these side effects are rare, and the general male population who take PDE5 inhibitors only have mild side effects.

In placebo-controlled clinical trials, the discontinuation rate due to adverse events was 3.4% for Levitra compared to 1.1% for placebo. Levitra is used to treat adult men (aged 18 years or over) with erectile dysfunction (sometimes called impotence), when they cannot get or keep a hard penis (erection) sufficient for satisfactory sexual activity. The typical starting dose for most people is 10 milligrams once per day taken 60 minutes before sexual activity. Your doctor can increase the dose to 20 milligrams maximum or decrease the dose to 5 milligrams if needed. For most individuals, the recommended dose of vardenafil regular tablets is 10 mg per day taken 60 minutes before intercourse.
Indinavir (800 mg t.i.d.) co-administered with LEVITRA 10 mg resulted in a 16-fold increase in vardenafil AUC, a 7-fold increase in vardenafil Cmax and a 2-fold increase in vardenafil half-life. It is recommended not to exceed a single 2.5 mg LEVITRA dose in a 24-hour period when used in combination with indinavir (see WARNINGS and DOSAGE AND ADMINISTRATION). Physicians should inform patients that there have been rare reports of prolonged erections greater than 4 hours and priapism (painful erections greater than 6 hours in duration) for LEVITRA and this class of compounds. Vardenafil may cause a mild and temporary drop in blood pressure. You may be at a higher risk if you have certain health conditions or take blood pressure medicines.
The dose may be increased to a maximum 20 mg or decreased to 5 mg based on efficacy and side effects. In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using Levitra and get medical help right away, or permanent problems could occur. Erythromycin (500 mg t.i.d.) produced a 4-fold increase in vardenafil AUC and a 3-fold increase in Cmax when co-administered with Levitra 5 mg in healthy volunteers.